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Care of the Pediatric Patient on Chronic Dialysis
Annabelle N Chua1, Bradley A Warady1
1Division of Nephrology, Department of Pediatrics, Duke University School of Medicine, Duke Children's Hospital, Durham, NC and Division of Nephrology, Dialysis and Transplantation, University of Missouri-Kansas City School of Medicine; Division of Nephrology, Children's Mercy Kansas City, Kansas City, MO.
Insights
Optimal care for pediatric end-stage renal disease (ESRD) patients on dialysis involves multidisciplinary teams and patient involvement. Focusing on dialysis adequacy and preventing complications improves survival and minimizes morbidity in children with ESRD.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
- Chronic Disease Management
Background:
- Pediatric end-stage renal disease (ESRD) management is complex, necessitating a comprehensive approach.
- Effective care requires collaboration among the dialysis team, patients, and caregivers.
- Children with ESRD have unique physiological and developmental considerations compared to adults.
Purpose of the Study:
- To review current recommendations and advances in the care of pediatric patients undergoing chronic dialysis.
- To emphasize the importance of patient and caregiver involvement in selecting appropriate dialysis modalities.
- To highlight strategies for minimizing ESRD-associated morbidity and mortality in children.
Main Methods:
- This review synthesizes current literature and clinical guidelines.
- It focuses on key aspects of pediatric dialysis care, including modality selection.
- Preventive measures and management of ESRD complications are discussed.
Main Results:
- Optimal dialysis involves meticulous attention to solute and fluid removal (dialysis adequacy).
- Management must address critical areas: anemia, growth, nutrition, bone disease, cardiovascular health, and neurocognitive development.
- Advances in dialysis care have significantly improved survival rates for pediatric patients.
Conclusions:
- Multidisciplinary care and shared decision-making are crucial for pediatric ESRD patients.
- Proactive management of complications and adherence to best practices enhance patient outcomes.
- Continuous advancements in dialysis therapies contribute to better long-term survival and quality of life for children with ESRD.
Abstract:
Optimal care of the pediatric end-stage renal disease (ESRD) patient on chronic dialysis is complex and requires multidisciplinary care as well as patient/caregiver involvement. The dialysis team, along with the family and patient, should all play a role in choosing the dialysis modality which best meets the patient's needs, taking into account special considerations and management issues that may be particularly pertinent to children who receive peritoneal dialysis or hemodialysis. Meticulous attention to dialysis adequacy in terms of solute and fluid removal, as well as to a variety of clinical manifestations of ESRD, including anemia, growth and nutrition, chronic kidney disease-mineral bone disorder, cardiovascular health, and neurocognitive development, is essential. This review highlights current recommendations and advances in the care of children on dialysis with a particular focus on preventive measures to minimize ESRD-associated morbidity and mortality. Advances in dialysis care and prevention of complications related to ESRD and dialysis have led to better survival for pediatric patients on dialysis.
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