A controlled study of plasma fatty acids in Indian patients with depressive episode
Bichitra Nanda Patra1, Sudhir K Khandelwal1, Rakesh K Chadda1
1Department of Psychiatry, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India.
Aim:
To study the plasma omega 3 and omega 6 fatty acid levels in patients with depressive episode and in matched healthy controls.
Method:
Thirty patients with first episode depression and thirty healthy matched control subjects were recruited from a tertiary care hospital setting. We measured plasma omega-3 and omega-6 fatty acid levels of the study and the control group.
Result:
There were no significant differences in plasma omega 3 fatty acid levels between study group and control group. The plasma omega 6 fatty acid levels of study group were significantly less than that of control group.
Conclusions:
The present study is an initial attempt to investigate the link between fatty acids and depression in a clinical setting in India. This comparative study with normal controls did not etiologically link these polyunsaturated fatty acids in this sample of depressive disorder.
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