Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

52.0K
Overview
52.0K
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

822
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
822
Ethical Dilemmas I01:17

Ethical Dilemmas I

2.1K
Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...
2.1K
Levels of Communication II: Organizational, Public, and Group Dynamics01:27

Levels of Communication II: Organizational, Public, and Group Dynamics

3.1K
Effective communication is the foundation of a good organization. Communication is the lifeblood of an organization that connects the group with messages. In an organization, communication occurs in upward, downward, and horizontal lines. Downward communication travels from the administrative and senior levels to the staff through official channels such as manuals, rules and regulations, and organizational charts. Staff members initiate upward communication, which is addressed to executives and...
3.1K
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

1.4K
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
1.4K
Social Proof00:52

Social Proof

32.4K
Social proof is a form of persuasion based on comparison and conformity. People compare their behavior and actions to what others are doing and will change to conform to do what their peers do.
32.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correlation of noninvasive near-infrared spectroscopy with outcomes in pediatric traumatic brain injury.

Journal of neurosurgery. Pediatrics·2026
Same author

Online communitarian appeals increase opposition to violent extremism.

PNAS nexus·2026
Same author

Implications of regional variations in climate change vulnerability and mitigation behaviour for social-climate dynamics.

Nature communications·2026
Same author

When simple is enough: Binary models capture social complexity in coupled human-environment systems.

Mathematical biosciences·2026
Same author

How deceptive online networks reached millions in the US 2020 elections.

Nature human behaviour·2026
Same author

Prejudice and objectivity, not social influence, determine long-term outcomes in coupled opinion-environment dynamics in polarized populations.

Journal of theoretical biology·2026
Same journal

The TaMYB55-TaSnRK1α1-TabZIP9 module confers heat stress tolerance in wheat.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Superstatistics approach to turbulent circulation fluctuations.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

A molecular timescale for evolution of cobamide biosynthesis.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Pierre Chambon, a pioneer of molecular biology and gene regulation in eukaryotes.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Granulosa cell glycogen fuels the avascular corpus luteum.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Synthetic essentiality of TRAIL/TNFSF10 in VHL-deficient renal cell carcinoma.

Proceedings of the National Academy of Sciences of the United States of America·2026
See all related articles

Related Experiment Video

Updated: Feb 17, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

1.6K

Critical dynamics in population vaccinating behavior.

A Demetri Pananos1, Thomas M Bury1, Clara Wang2

  • 1Department of Applied Mathematics, University of Waterloo, Waterloo, ON, Canada N2L 3G1.

Proceedings of the National Academy of Sciences of the United States of America
|December 13, 2017
PubMed
Summary
This summary is machine-generated.

Vaccine refusal dynamics show critical slowing down before outbreaks, indicating a tipping point. After an outbreak, populations adapt, leading to critical speeding up and increased resilience.

Keywords:
early warning signalsmachine learningonline social mediasocioecological systemsvaccine refusal

More Related Videos

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

11.3K
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.7K

Related Experiment Videos

Last Updated: Feb 17, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

1.6K
Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

11.3K
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.7K

Area of Science:

  • Complex systems science
  • Epidemiology
  • Public health

Background:

  • Vaccine refusal poses a significant threat to public health, risking disease resurgence and hindering global eradication efforts.
  • Vaccinating decisions are part of a complex, coupled system where behavior and disease dynamics interact, potentially exhibiting critical phenomena near tipping points.

Purpose of the Study:

  • To investigate critical phenomena, specifically critical slowing down, in population vaccinating behavior preceding a measles outbreak.
  • To analyze the adaptive response of populations to disease outbreaks and its impact on system resilience.

Main Methods:

  • Collected and geocoded tweets related to the measles-mumps-rubella vaccine.
  • Utilized machine learning algorithms for sentiment classification of tweets.
  • Extracted and analyzed measles-related Google search data.
  • Employed mathematical modeling of disease transmission and vaccine sentiment.

Main Results:

  • Observed critical slowing down in social and search data preceding the 2014-2015 Disneyland measles outbreak at state and national levels.
  • Identified that critical slowing down intensified as vaccine uptake declined, signaling an approach to a tipping point.
  • Documented 'critical speeding up' post-outbreak, indicating increased population resilience due to adaptive behavior changes.

Conclusions:

  • Population vaccinating behavior near disease elimination thresholds exhibits characteristics of critical phenomena.
  • Digital social data analysis can reveal critical patterns, potentially identifying populations at risk of widespread vaccine refusal.
  • Understanding these critical dynamics is crucial for predicting and mitigating vaccine-preventable disease outbreaks.