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Study on Effects of Titanium Surface Microporous Coatings Containing Zinc on Osteoblast Adhesion and Its
Quan-Ming Zhao1, Guang-Zhong Li2, Hao-Ming Zhu1
1Department of Orthopedic Surgery, Wuxi People's Hospital, Nanjing Medical University, Wuxi City, Jiangsu Province 214023, China.
Abstract:
Metal surface structure/biomedical function integration is the current research focus. In previous studies, we have successfully prepared the microporous coatings containing zinc on the pure titanium surface by MAO. In the study, osteoblasts were seeded on the surface of the microporous coatings containing zinc and the adhesion of osteoblasts were evaluated, and the antibacterial activity of the microporous coatings containing zinc is observed through in vitro bacterial experiments. The result indicates that the adhesion ability of osteoblasts on the surface of microporous coatings containing zinc was very good, and the coatings could obviously inhibit the growth of Staphylococcus aureus and had good antibacterial activity. In conclusion, the microporous coatings containing zinc on titanium surface have good osteogenic and antibacterial properties and have good application prospect.
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