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The Successful Treatment of a Case of Linear Psoriasis with Ixekizumab

Sara Ghoneim1, Alvaro J Ramos-Rodriguez2, Fernando Vazquez de Lara2

  • 1Saba University School of Medicine, The Bottom, Netherlands.

Case Reports in Dermatological Medicine
|December 13, 2017
PubMed

Linear psoriasis is an unusual clinical variation of psoriasis that manifests segmentally along the lines of Blaschko. A major differential diagnosis is inflammatory linear verrucous epidermal nevus (ILVEN). The treatment of linear psoriasis is often challenging, with inadequate response to biological agents reported in the literature. We report a case of a 25-year-old African-American female who presented with asymptomatic hyperkeratotic papules along the lines of Blaschko and was subsequently diagnosed with linear psoriasis. After failing conventional treatment regimens, the patient received a trial of ixekizumab with complete resolution of cutaneous lesions reported after 4 months and only 8 doses of the anti-IL-17 biologic agent.

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