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Associations between left ventricular diastolic function and right ventricular function in patients with and without
Tsumugi Oki1,2, Hidekazu Tanaka3, Takamitsu Imanishi2
1Division of Laboratory Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Journal of Echocardiography
|December 13, 2017
Summary
Right ventricular function closely correlates with left ventricular diastolic function in patients with reduced ejection fraction. This association was not observed in patients with preserved ejection fraction, suggesting different management strategies.
Area of Science:
- Cardiology
- Echocardiography
- Heart Failure
Background:
- Right ventricular (RV) and left ventricular (LV) function are critical in heart failure.
- Understanding the interplay between RV function and LV diastolic function is essential for patient management.
Purpose of the Study:
- To investigate the associations between RV function and LV diastolic function.
- To compare these associations in patients with reduced versus preserved LV ejection fraction (LVEF).
Main Methods:
- 139 patients underwent echocardiography.
- LV diastolic function assessed by E/e' ratio; RV function by RV index of myocardial performance (RIMP).
- Patients categorized into reduced LVEF (<50%) and preserved LVEF (≥50%) groups.
Main Results:
- RV function (RIMP) significantly correlated with LV diastolic function (E/e') in the reduced LVEF group (r=0.47, p=0.003).
- No significant correlation was found in the preserved LVEF group (r=0.04, p=0.68).
- RIMP was an independent determinant of E/e' in reduced LVEF, while age and gender were determinants in preserved LVEF.
Conclusions:
- RV function is closely linked to LV diastolic function in patients with reduced LVEF.
- This relationship differs significantly in patients with preserved LVEF.
- Findings have clinical implications for managing patients with reduced LVEF.
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