[Confirming Indicators of Qualitative Results by Chromatography-mass Spectrometry in Biological Samples]
S D Liu1, D M Zhang2, W Zhang2
1School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China.
Abstract:
Because of the exist of complex matrix, the confirming indicators of qualitative results for toxic substances in biological samples by chromatography-mass spectrometry are different from that in non-biological samples. Even in biological samples, the confirming indicators are different in various application areas. This paper reviews the similarities and differences of confirming indicators for the analyte in biological samples by chromatography-mass spectrometry in the field of forensic toxicological analysis and other application areas. These confirming indicators include retention time (RT), relative retention time (RRT), signal to noise (S/N), characteristic ions, relative abundance of characteristic ions, parent ion-daughter ion pair and abundance ratio of ion pair, etc.
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