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Necrosis01:16

Necrosis

6.7K
Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become...
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Burn Injuries01:22

Burn Injuries

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Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
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Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
430
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

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The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
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Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

488
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
488
Pneumothorax-I01:26

Pneumothorax-I

1.5K
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
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Related Experiment Video

Updated: Feb 17, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
08:16

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

Published on: March 16, 2022

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Gas gangrene.

Lt Mark B Stephens

    Postgraduate Medicine
    |December 13, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Clostridial myonecrosis, or gas gangrene, is a rare but rapidly fatal infection following trauma. Early recognition, surgical debridement, antibiotics, and hyperbaric oxygen therapy are critical for effective management.

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    High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
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    Induction of Cerebral Arterial Gas Embolism in Rat
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    Area of Science:

    • Medical Microbiology
    • Infectious Diseases
    • Trauma Surgery

    Background:

    • Clostridial myonecrosis, commonly known as gas gangrene, is a severe and uncommon complication of traumatic injuries.
    • The rapid progression of this infection poses a significant threat to patient survival, necessitating prompt medical intervention.

    Purpose of the Study:

    • To illustrate the clinical presentation and management of clostridial myonecrosis.
    • To review current data on effective treatment strategies for gas gangrene.

    Main Methods:

    • Case presentation of a patient with clostridial myonecrosis.
    • Discussion of established treatment modalities including surgical debridement and antibiotics.
    • Evaluation of hyperbaric oxygen therapy as an adjunct treatment.

    Main Results:

    • Gas gangrene requires immediate and aggressive medical and surgical intervention.
    • Hyperbaric oxygen therapy demonstrates synergistic benefits when combined with standard treatments.

    Conclusions:

    • Prompt diagnosis and treatment are paramount in managing potentially fatal clostridial myonecrosis.
    • A multimodal approach, including surgery, antibiotics, and hyperbaric oxygen, offers the best outcomes for patients with gas gangrene.