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Hypertrophic Cardiomyopathy-Past, Present and Future.
Alphonsus C Liew1, Vassilios S Vassiliou2,3,4, Robert Cooper5
1Royal Bournemouth Hospital, Bournemouth BH7 7DW, UK. Alphonsus.liew@hotmail.com.
Journal of Clinical Medicine
|December 13, 2017
Summary
Hypertrophic cardiomyopathy (HCM), a common genetic heart condition, has seen significant advancements in understanding, diagnosis, and management since its initial description. This review covers its history, current guidelines, and future developments.
Area of Science:
- Cardiology
- Genetics
- Medical History
Background:
- Hypertrophic cardiomyopathy (HCM) is the most prevalent genetic cardiomyopathy, affecting approximately 1 in 500 individuals.
- The understanding of HCM has evolved significantly since the first pathological case series in 1957.
- This condition presents complex diagnostic and management challenges.
Purpose of the Study:
- To provide a historical overview of the understanding of hypertrophic cardiomyopathy.
- To review current diagnostic methods and treatment options for HCM.
- To identify evidence gaps and discuss emerging developments in HCM research and care.
Main Methods:
- Literature review of historical pathological findings.
- Analysis of current diagnostic guidelines and treatment strategies.
- Discussion of recent research and future directions in HCM.
Main Results:
- Detailed historical progression of HCM knowledge from initial findings to current understanding.
- Comprehensive overview of established diagnostic tools and therapeutic interventions.
- Identification of areas requiring further research and promising novel approaches.
Conclusions:
- HCM understanding has advanced considerably, improving patient outcomes.
- Current guidelines provide a framework for diagnosis and management.
- Future research holds promise for more targeted and effective HCM therapies.
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