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Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
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Imaging analysis of superficial soft tissue lymphomas
In Sook Lee1, You Seon Song1, Seung Hyun Lee1
1Department of Radiology, Pusan National University Hospital, Biomedical Research Institute, 179, Gudeok-ro, Seo-gu, Busan 602-739, Republic of Korea; Pusan National University School of Medicine, Busan, Republic of Korea.
Clinical Imaging
|December 13, 2017
Summary
Imaging superficial soft tissue lymphomas, particularly skin lymphomas, revealed non-specific findings. Multiple nodular lesions with ill-defined margins may suggest this diagnosis.
Area of Science:
- Radiology
- Oncology
- Dermatology
Background:
- Superficial soft tissue lymphomas involve the skin and subcutaneous layers.
- Accurate imaging is crucial for diagnosis and management.
Purpose of the Study:
- To characterize imaging findings in superficial soft tissue lymphomas.
- To correlate imaging features with pathological confirmation.
Main Methods:
- Retrospective analysis of 44 pathologically confirmed superficial lymphoma lesions.
- Evaluation of lesion characteristics: size, margin, location, morphology, homogeneity, and multiplicity.
Main Results:
- Nodular morphology was most common (47.7%), often with a streaky appearance.
- Ill-defined margins (59.1%) and homogeneous patterns (79.5%) were frequently observed.
Conclusions:
- Imaging findings for superficial soft tissue lymphomas are generally non-specific.
- Consider superficial soft tissue lymphoma in cases with multiple nodular lesions and ill-defined margins.
