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Updated: Feb 17, 2026

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
Imaging analysis of superficial soft tissue lymphomas
In Sook Lee1, You Seon Song1, Seung Hyun Lee1
1Department of Radiology, Pusan National University Hospital, Biomedical Research Institute, 179, Gudeok-ro, Seo-gu, Busan 602-739, Republic of Korea; Pusan National University School of Medicine, Busan, Republic of Korea.
Purpose:
To describe imaging findings in superficial soft tissue lymphomas, especially those located in the skin and subcutaneous layer.
Materials And Methods:
This study included 44 pathologically confirmed superficial lymphoma lesions. Imaging analysis included the size, margin, location, morphology, homogeneity and multiplicity.
Results:
A nodular form was the most common (21/44, 47.7%) morphology, and of them, 18 demonstrated a streaky appearance. Most of the lesions demonstrated ill-defined margins (26/44, 59.1%) and homogeneous patterns (35/44, 79.5%).
Conclusions:
The imaging findings of superficial soft tissue lymphomas were non-specific. However, if images show multiple nodular lesions with ill-defined margins, we should consider this diagnosis.

