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Structural insights into the mechanisms of CNBD channel function

Zachary M James1, William N Zagotta2

  • 1Department of Physiology and Biophysics, University of Washington, Seattle, WA.

The Journal of General Physiology
|December 14, 2017
PubMed
Summary

Cyclic nucleotide-binding domain (CNBD) channels, crucial for physiology, show diverse functions despite structural similarities. Recent structures illuminate their roles in ion selectivity and gating mechanisms.

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