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Published on: August 4, 2011
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Retinoblastoma presenting as total hyphema: Three year follow-up
Saemah Nuzhat Zafar1, Naima Zaheer1, Mumtaz Ahmad Khan2
1Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan.
Summary
This case study highlights a rare presentation of retinoblastoma (a childhood eye cancer) as total hyphema in a 7-month-old. Successful treatment involved enucleation and chemotherapy for advanced group E retinoblastoma.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Cancer Research
Background:
- Retinoblastoma is the most common primary intraocular malignancy in children.
- Total hyphema is an exceptionally rare presenting sign of retinoblastoma.
- Delayed diagnosis can lead to advanced disease and poorer outcomes.
Purpose of the Study:
- To report a rare case of retinoblastoma presenting with total hyphema.
- To discuss factors contributing to delayed diagnosis and treatment.
- To emphasize the importance of early detection in retinoblastoma management.
Main Methods:
- Case report of a 7-month-old infant with unilateral group E retinoblastoma.
- Description of treatment including enucleation and adjuvant chemotherapy.
- Review of potential factors leading to delayed presentation.
Main Results:
- Successful treatment of unilateral group E retinoblastoma with enucleation and adjuvant chemotherapy.
- The fellow eye remained unaffected during a 3-year follow-up.
- Identification of factors contributing to delayed diagnosis in this case.
Conclusions:
- Spontaneous hyphema can indicate advanced retinoblastoma, necessitating prompt evaluation.
- Early detection and timely intervention are crucial for favorable outcomes in retinoblastoma.
- This case underscores the variability in retinoblastoma presentation and the need for vigilance.
