Related Experiment Video
Updated: Feb 17, 2026
Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
Factors affecting the outcomes of direct pulp capping using Biodentine
Mariusz Lipski1, Alicja Nowicka2, Katarzyna Kot3
1Department of Preclinical Conservative Dentistry and Preclinical Endodontics, Pomeranian Medical University of Szczecin, Al. Powstańców Wlkp. 72, 70-111, Szczecin, Poland. lipam@pum.edu.pl.
Introduction:
This study aimed to evaluate the prognostic value of factors with regard to the treatment outcome of direct pulp capping using Biodentine (Septodont, Saint-Maur-des-Fossés, France), in permanent teeth in which the pulps were exposed during caries removal.
Methods:
Between 2010 and 2014, 112 teeth with deep carious lesions underwent direct pulp capping. The patients were followed up at 2-3 months and 1-1.5 years with a routine examination on both recall visits. Periapical radiographs were taken at 1-1.5 years. Lack of patient complaints, positive reactions to cold and electric testing, no sensitivity to percussion, and no widening of the periapical ligament indicated success. The Fisher exact test was used for statistical analysis. The significance level was P = .05.
Results:
Eighty-six teeth were available for 1-1.5 years follow-up. The overall success rate was 82.6%. Only age had a significant effect on the pulpal survival rate: the success rate was 90.9% in patients younger than 40 years and 73.8% in patients 40 years or older (P = .0480). Sex, initial or secondary caries treatment, occlusal or cervical/proximal caries, delayed placement of permanent filling, tooth position, and arch type did not influence the outcome.
Conclusions:
A patient's age influenced the outcome of direct pulp capping using this new calcium silicate cement.
Clinical Relevance:
Asymptomatic vital permanent teeth with cariously exposed pulp can be treated successfully by direct pulp capping using Biodentine.
