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Updated: Feb 17, 2026

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating
Published on: October 11, 2016
Two-dimensional antiscatter grid: A novel scatter rejection device for Cone-beam computed tomography
Timur Alexeev1, Brian Kavanagh1, Moyed Miften1
1Department of Radiation Oncology, University of Colorado School of Medicine, 1665 Aurora Court, Suite 1032, Mail stop F-706 , Aurora, CO, 80045, USA.
A novel two-dimensional antiscatter grid (2D-ASG) significantly improves image quality in Flat Panel Detector-based Cone-beam computed tomography (CBCT). This new grid reduces scatter radiation, enhancing contrast-to-noise ratio and CT number accuracy for better soft tissue visualization.
Area of Science:
- Medical Imaging
- Radiological Physics
- Cone-Beam Computed Tomography
Background:
- Scattered radiation is a primary factor degrading image quality in Flat Panel Detector (FPD)-based Cone-beam computed tomography (CBCT).
- Reducing scatter intensity is crucial for improving CBCT image fidelity and diagnostic accuracy.
Purpose of the Study:
- To investigate a novel two-dimensional antiscatter grid (2D-ASG) for scatter reduction in CBCT.
- To demonstrate the efficacy of a 2D-ASG prototype in enhancing CBCT image quality.
Main Methods:
- A 2D-ASG prototype made of tungsten was additively manufactured and mounted on a Varian TrueBeam CBCT system.
- CBCT projections were acquired using an offset detector geometry, with angle-specific gain correction applied.
- Image quality was assessed by measuring contrast-to-noise ratio (CNR) and CT number accuracy, comparing 2D-ASG with no antiscatter grid (NO-ASG) and 1D-ASG.
Main Results:
- The 2D-ASG prototype achieved significant improvements in contrast resolution compared to NO-ASG and 1D-ASG.
- CNR of material inserts improved by up to 86% (vs. NO-ASG) and 54% (vs. 1D-ASG).
- CT number underestimation in water-equivalent material was reduced by up to 325 HU (vs. NO-ASG) and 179 HU (vs. 1D-ASG) with the 2D-ASG.
Conclusions:
- The first CBCT imaging experiments with a 2D-ASG prototype were successfully conducted.
- The 2D-ASG demonstrated significantly higher CT number accuracy, improved CNR, and reduced scatter-induced artifacts.
- The 2D-ASG holds potential for enhanced soft tissue visualization and novel clinical applications in CBCT.
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