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Updated: Feb 17, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Photoprotection by sunscreen depends on time spent on application
Ida M Heerfordt1, Linnea R Torsnes1, Peter A Philipsen1
1Department of Dermatology, Bispbjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Applying sunscreen for longer ensures adequate coverage. This study found a consistent amount of sunscreen applied per minute, highlighting the importance of application time for effective photoprotection.
Area of Science:
- Dermatology
- Photoprotection research
Background:
- Effective sunscreen use requires sufficient quantity and reapplication.
- The impact of application time on sunscreen effectiveness was previously unstudied.
Purpose of the Study:
- To investigate the relationship between time spent applying sunscreen and the quantity used.
- To assess this relationship for both initial and subsequent sunscreen applications.
Main Methods:
- Thirty-one volunteers applied sunscreen twice under controlled laboratory conditions.
- Time and quantity of sunscreen applied were measured for each application.
- Body surface area (BSA) was estimated to calculate sunscreen density.
Main Results:
- A linear correlation was found between application time and sunscreen quantity used (P < .0001).
- Participants applied a consistent 2.21 grams of sunscreen per minute.
- Mean application density was 0.71 mg/cm² after the first application and 1.27 mg/cm² after the second.
Conclusions:
- A constant rate of sunscreen application per minute was observed for both first and second applications.
- Measuring application time can inform studies on real-world sunscreen distribution and effectiveness.
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