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ZikaPLAN: Zika Preparedness Latin American Network
A Wilder-Smith1, R Preet1, K E Renhorn1
1a Unit of Epidemiology and Global Health, Department of Public Health and Clinical Medicine , Umeå University , Umeå Sweden.
Global Health Action
|December 14, 2017
Summary
The ZikaPLAN consortium is building a research network to address Zika virus (ZIKV) knowledge gaps and enhance preparedness for emerging infectious diseases. This initiative focuses on clinical studies, laboratory research, and community engagement to inform policy and build regional capacity.
Area of Science:
- Global Health
- Infectious Diseases
- Virology
Background:
- The Zika virus (ZIKV) outbreak highlighted critical knowledge gaps and the need for a coordinated regional research response.
- Existing research efforts required enhancement to address both current ZIKV challenges and future emerging infectious disease threats.
Purpose of the Study:
- To establish the Zika Preparedness Latin American Network (ZikaPLAN) consortium to address ZIKV knowledge gaps and build regional research capacity.
- To conduct clinical and laboratory research on ZIKV, focusing on congenital Zika virus syndrome, neurological complications, and transmission routes.
- To strengthen surveillance, develop evidence-informed policies, and foster long-term preparedness for emerging infectious diseases in the region.
Main Methods:
- Formation of a multi-regional consortium (ZikaPLAN) with 25 partners across Latin America, North America, Africa, Asia, and Europe.
- Conducting clinical studies on congenital Zika virus syndrome, neurological complications in children and adults, and Guillain-Barré Syndrome surveillance.
- Performing laboratory research on neurotropism, sexual transmission, severe disease determinants, and viral fitness, complemented by social messaging and vector control strategies.
Main Results:
- The ZikaPLAN consortium has been established, integrating diverse expertise to address ZIKV research needs.
- Clinical and laboratory research protocols are being implemented to define the spectrum of ZIKV-related diseases and understand viral pathogenesis.
- Initiatives for capacity building, knowledge sharing, and policy development are underway to enhance regional preparedness for future infectious disease outbreaks.
Conclusions:
- ZikaPLAN is a vital initiative for advancing ZIKV research and strengthening regional capacity to respond to emerging infectious diseases.
- The consortium's integrated approach, combining clinical, laboratory, and policy-relevant research, will provide critical evidence for public health interventions.
- By leveraging the ZIKV response, the project aims to build sustainable, long-term research and response capabilities in the region.
