Proteomics in Pathology
Related Experiment Video
Updated: Feb 17, 2026
A Streamlined Approach for Mass Spectrometry-Based Proteomics Using Selected Tissue Regions
Published on: April 18, 2025
Rémi Longuespée1, Rita Casadonte2, Kristina Schwamborn3
1Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Abstract:
Proteomic approaches are of growing importance in the biologist's toolbox. It greatly benefited from past and recent advances in sampling, chemical processing, mass spectrometry (MS) instrumentation, and data processing. MS-based analysis of proteins is now in the process of being translated in pathology for objective diagnoses. In this viewpoint, we present the workflows that we think are the most promising for applications in pathology. We also comment what we think are prerequisites for a successful translational implementation.
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