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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Is it severe asthma or asthma with severe comorbidities?
Luisa Brussino1, Paolo Solidoro2, Giovanni Rolla1
1Allergy and Clinical Immunology, University of Torino and Mauriziano Hospital.
Journal of Asthma and Allergy
|December 15, 2017
Summary
Severe asthma management requires considering comorbidities. Addressing conditions like rhinosinusitis and obesity can improve asthma control, moving beyond just high-dose inhaled corticosteroids (ICSs).
Area of Science:
- Pulmonology
- Allergy and Immunology
- Clinical Medicine
Background:
- Severe asthma is defined by treatment needs, not distinct biology.
- Current definitions lack specificity, relying on general symptoms.
- Asthma symptoms can be mimicked by comorbidities, leading to misdiagnosis.
Purpose of the Study:
- To highlight the limitations in defining severe asthma.
- To emphasize the role of comorbidities in asthma management.
- To advocate for a focus on diagnosing and treating comorbidities in severe asthma patients.
Main Methods:
- Review of current severe asthma definitions and clinical practices.
- Analysis of symptom overlap between asthma and common comorbidities.
- Discussion of the impact of comorbidities on asthma control.
Main Results:
- The current definition of severe asthma does not identify specific biological markers.
- Common asthma symptoms like wheezing and dyspnea can stem from comorbidities.
- Over-reliance on inhaled corticosteroids (ICSs) without addressing comorbidities leads to poor asthma control.
Conclusions:
- Clinicians should prioritize the diagnosis of comorbidities in severe asthma.
- Specific treatments for comorbidities can significantly improve asthma control.
- A shift in focus towards comorbidities is crucial for effective severe asthma management.
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