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Predictors of coverage of the national maternal pertussis and infant rotavirus vaccination programmes in England

L Byrne1, C Ward1, J M White1

  • 1Immunisation, Hepatitis and Blood Safety Department,National Infections Service, Public Health England,London,UK.

Epidemiology and Infection
|December 15, 2017
PubMed

Insights

Maternal pertussis and infant rotavirus vaccination coverage varied significantly by ethnicity and deprivation in England. These factors, alongside location, influenced program uptake, highlighting disparities in public health interventions.

Area of Science:

  • Public Health
  • Vaccinology
  • Health Services Research

Background:

  • Maternal pertussis vaccination was introduced in England in October 2012 due to a pertussis outbreak.
  • An infant rotavirus vaccination program was implemented in England in July 2013.
  • Understanding vaccination coverage variations is crucial for public health equity.

Purpose of the Study:

  • To assess variations in maternal pertussis and infant rotavirus vaccination coverage in England.
  • To identify predictors of vaccination coverage, including ethnicity, socioeconomic status (Index of Multiple Deprivation - IMD), and geographic location (NHS England Local Team - LT).

Main Methods:

  • Utilized national vaccine coverage datasets for England.
  • Calculated vaccine coverage overall and stratified by LT, ethnicity, and IMD quintile.
  • Employed binomial regression to compare coverage rates and identify significant predictors.

Main Results:

  • Significant coverage disparities were observed across different ethnic groups for both vaccines.
  • Maternal pertussis coverage was lowest in black-other and black-Caribbean women (-16.3%, -15.4%).
  • Infant rotavirus coverage showed largest deficits in 'other', white-Irish, and black-Caribbean infants (-13.9%, -12.1%, -10.7%).
  • Coverage was lowest in the London Local Team area for both programs.
  • Vaccination coverage decreased with increasing socioeconomic deprivation, with the most deprived quintile showing lower coverage (14.0% for pertussis, 4.4% for rotavirus) compared to the least deprived.
  • Ethnicity and deprivation were significant predictors of coverage but did not fully explain geographical variations.

Conclusions:

  • Ethnicity and socioeconomic deprivation are key predictors of maternal pertussis and infant rotavirus vaccination coverage in England.
  • Geographical variations in coverage exist and are partly explained by demographic and socioeconomic factors.
  • Targeted interventions are needed to address disparities and improve vaccine uptake in underrepresented populations and deprived areas.

Keywords:
Ethnicityinequalitiesvaccination

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