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Related Experiment Video

Updated: Feb 16, 2026

Video Tracking Protocol to Screen Deterrent Chemistries for Honey Bees

Video Tracking Protocol to Screen Deterrent Chemistries for Honey Bees

Published on: June 12, 2017

DEET as a feeding deterrent.

WeiYu Lu¹, Justin K Hwang¹, Fangfang Zeng¹

¹Department of Molecular and Cellular Biology, University of California Davis, Davis, CA, United States of America.

|December 15, 2017

Summary

This summary is machine-generated.

N,N-diethyl-3-methylbenzamide (DEET) and permethrin significantly reduce mosquito feeding time by acting as gustatory feeding deterrents. Picaridin showed a weaker deterrent effect in this study.

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Area of Science:

Entomology
Insecticide Research
Chemical Ecology

Background:

N,N-diethyl-3-methylbenzamide (DEET) is a widely used insect repellent with known spatial and contact repellent properties.
Previous research indicated DEET's ability to reduce mosquito blood-feeding, but the specific mechanism as a gustatory deterrent was not isolated from other repellent effects.

Purpose of the Study:

To investigate the feeding deterrent properties of DEET, picaridin, and permethrin on mosquitoes, independent of spatial or contact repellency.
To quantify the effect of these compounds on mosquito feeding behavior when ingested.

Main Methods:

Development of a specialized behavioral assay to assess feeding deterrence.
Using the southern house mosquito (Culex quinquefasciatus) exposed to blood treated with DEET, picaridin, or permethrin, covered by a membrane.
Measurement of mosquito landing, contact duration, and feeding times.

Main Results:

DEET (0.1% and 1%) significantly reduced mosquito feeding times, indicating a gustatory deterrent effect.
Permethrin also significantly reduced feeding times, confirming its role as a feeding deterrent.
Picaridin showed a significant feeding deterrent effect only at a 5% concentration, but not at 1%.

Conclusions:

DEET and permethrin function as effective gustatory feeding deterrents against mosquitoes.
Picaridin exhibits feeding deterrent properties, though less potent than DEET or permethrin at tested concentrations.
The developed assay effectively isolates and measures the gustatory feeding deterrent effects of insect repellents.