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Neuronal loss in lumbar dorsal root ganglia after proximal compared to distal sciatic nerve resection: a quantitative
1Department of Anatomy, Karolinska Institutet, Stockholm, Sweden.
Brain Research
|January 23, 1989
Abstract:
The effects of unilateral sciatic nerve resections at proximal (thigh) or distal (proximal calf) locations on L4-L6 dorsal root ganglion (DRG) neuronal numbers have been studied in adult rats. Proximal nerve resection gave rise to a mean DRG neuronal loss of 27%, whereas in distal lesions a mean cell loss of 7% was found. This difference in cell loss between proximal and distal sciatic nerve resections is highly significant (P less than 0.001).
