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EMBOPRO--an automatically generated protein sequence database.

R Stulich1, K Rohde

  • 1Department of Molecular Biophysics, Central Institute of Molecular Biology of the Academy of Sciences of the GDR, Berlin-Buch.

Computer Applications in the Biosciences : CABIOS
|February 1, 1989
PubMed
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We developed an automated protein sequence database by translating new EMBL releases. This database aids in identifying novel proteins and ensures reliable nucleotide sequence data for research.

Area of Science:

  • Bioinformatics
  • Molecular Biology
  • Genomics

Background:

  • Accurate protein identification relies on comprehensive sequence databases.
  • Existing databases require frequent updates to incorporate new genomic data.

Purpose of the Study:

  • To present an automatically generated protein sequence database.
  • To facilitate the identification of newly sequenced proteins through comparison.

Main Methods:

  • Periodical translation of new EMBL database releases using a custom program.
  • Assessment of potential translation errors and nucleotide sequence data reliability.
  • Comparative analysis against established protein sequence databases.

Main Results:

Related Experiment Videos

  • Demonstrated the feasibility of an automatically updated protein sequence database.
  • Evaluated the reliability of nucleotide sequence data from EMBL releases.
  • Provided a comparison of the generated database with existing resources.

    • Conclusions:

    • An automatically generated protein sequence database is a valuable tool for protein identification.
    • The nucleotide sequence data from EMBL releases exhibits high reliability.
    • The developed database offers a reliable alternative for protein sequence comparison.