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Related Experiment Video

Updated: Feb 16, 2026

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

Published on: August 8, 2014

Desquamative gingivitis mimicking mild gingivitis.

Shravanthi Raghav Yajamanya¹, Praveen Jayaram¹, Anirban Chatterjee¹

¹Department of Periodontology and Oral Implantology, The Oxford Dental College, Bengaluru, Karnataka, India.

Journal of Indian Society of Periodontology

|December 16, 2017

Summary

This summary is machine-generated.

This case report identifies pemphigus as the cause of chronic, episodic gingival inflammation. Early diagnosis through meticulous oral examination is crucial for timely treatment of this autoimmune condition.

Keywords:

Desquamative gingivitis Tzanck cell gingivitis intraepithelial split pemphigus

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Area of Science:

Oral Medicine
Dermatology
Pathology

Background:

Episodic gingival inflammation can mimic common conditions like gingivitis.
Persistent or unusual oral symptoms warrant further investigation beyond initial clinical presentation.

Observation:

A 33-year-old female presented with a year-long history of mild, intermittent gingival pain and burning.
Clinical examination initially suggested a mild form of gingivitis without systemic signs.

Findings:

Gingival biopsy revealed Tzanck cells and intraepithelial splitting.
These histological findings are indicative of pemphigus, an autoimmune blistering disease.

Implications:

Meticulous gingival examination is vital for detecting underlying systemic diseases.
Early diagnosis of conditions like pemphigus through oral pathology enables prompt and effective treatment.