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Updated: Feb 16, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
39.5K
Update on Current Care Guideline: Psoriasis (skin and joints)
Duodecim; Laaketieteellinen Aikakauskirja
|December 16, 2017
Summary
Psoriasis, an immune-mediated inflammatory disease, increases risks for cardiovascular diseases and diabetes. Effective long-term treatments, including new biologics, are crucial for managing this chronic condition and its comorbidities.
Area of Science:
- Immunodermatology
- Rheumatology
- Cardiology
Background:
- Psoriasis is a chronic, immune-mediated inflammatory skin and joint disorder.
- Moderate-to-severe psoriasis is linked to increased risks of cardiovascular diseases and diabetes.
- Systemic inflammation in psoriasis mirrors that in rheumatoid arthritis, necessitating long-term treatment strategies.
Purpose of the Study:
- To review long-term treatment data for psoriasis.
- To highlight the importance of managing comorbidities in psoriasis patients.
- To discuss recent advancements in biologic therapies for psoriasis.
Main Methods:
- Review of long-term treatment data from clinical study extensions.
- Analysis of data from independent patient registries.
- Evaluation of the impact of systemic inflammation on comorbidities.
Main Results:
- Psoriasis patients face independent risks for cardiovascular diseases and diabetes.
- Screening and management of cardiovascular risk factors are strongly recommended.
- New biologic drugs offer potential for long-term psoriasis management.
Conclusions:
- Effective long-term management is essential for psoriasis, addressing both skin/joint symptoms and systemic comorbidities.
- Ongoing monitoring and treatment of cardiovascular risk factors are critical.
- Recent advancements in biologic therapies show promise for improved patient outcomes.
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