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Updated: Feb 16, 2026

Development and Characterization of Fusidic Acid-Loaded Alginate-Aloe vera Based Hydrogel FilmWound Healing
Published on: December 13, 2024
Developing antimicrobial calcium alginate fibres from neem and papaya leaves extract
F Hussain1, M F Khurshid2, R Masood3
1Lecturer, Department of Materials and Testing, National Textile University, Faisalabad 37610, Pakistan.
Objective:
The aim of this study was to evaluate an alternative approach to developing antimicrobial alginate fibres using plant extracts, such as those from neem and papaya leaves.
Method:
Aqueous leaves extract from neem, papaya and their hybrid combinations were used as solvent to develop sodium alginate fibres. Sodium alginate polymer containing these extracts was extruded in a calcium chloride (CaCl2) bath to develop neem (NE), papaya (PE) and their hybrid combinations-based calcium alginate fibres (H-1 to H-5). The surface morphology, spectra, liquid absorption, tensile strength and antimicrobial activity of these developed fibres were measured.
Results:
NE fibre showed greater tensile strength than PE. The liquid absorption property of all developed fibres decreased, but showed antibacterial properties against Staphylococcus aureus and reduced bacterial growth up to 85% when compared with pure calcium alginate fibre.
Conclusion:
Neem, papaya and hybrid extract-based calcium alginate fibres have the potential to be used as wound dressings.

