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Hot Off the Press: SGEM#196: Gastroparesis-I Feel Like Throwing Up
Corey Heitz1, Justin Morgenstern2, William K Milne3
1Lewis Gale Medical Center, Salem, Salem, VA.
Insights
Haloperidol significantly improved pain and nausea in emergency department patients with gastroparesis compared to placebo. Conventional therapy was used in both groups, showing haloperidol
Area of Science:
- Emergency Medicine
- Gastroenterology
- Clinical Pharmacology
Background:
- Gastroparesis presents significant challenges in emergency departments.
- Effective symptom management for gastroparesis is crucial for patient outcomes.
Purpose of the Study:
- To evaluate the efficacy of haloperidol in managing acute gastroparesis symptoms.
- To compare haloperidol plus conventional therapy against placebo plus conventional therapy.
Main Methods:
- A randomized controlled trial was conducted.
- Participants received either haloperidol or placebo alongside conventional therapy.
- Primary outcomes included pain and nausea scores at 1 hour.
Main Results:
- Haloperidol group showed significant improvement in pain and nausea scores.
- The placebo group did not demonstrate significant symptom improvement.
- Quality assessment and social media commentary were also summarized.
Conclusions:
- Haloperidol is an effective treatment for acute gastroparesis symptoms in the emergency department.
- Further research may explore long-term effects and optimal dosing.
Abstract:
This randomized controlled trial compared haloperidol along with conventional therapy to placebo along with conventional therapy for gastroparesis in the emergency department. The primary outcomes of pain and nausea scores at 1 hour were significantly improved in the haloperidol group, but not in the placebo group. In this summary, we discuss a quality assessment of the article and summarized the social media commentary from the blog post/podcast.
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