Related Experiment Video
Updated: Feb 16, 2026
High-Throughput Dissociation and Orthotopic Implantation of Breast Cancer Patient-Derived Xenografts
Published on: December 20, 2024
Recurrent malignant phyllodes tumor of the breast: A case report
Qinqin Wang1, Jing Su, Yutao Lei
1Department of Breast Surgery, Peking University International Hospital Department of Pathology, Peking University Health Science Center Department of General Surgery, Peking University Third Hospital, Beijing, China.
Rationale:
Phyllodes tumor is a rare fibro epithelial neoplasm of the breast. They resemble fibroadenomas clinically and can be mistakenly ignored sometimes.
Patient Concerns:
We report the case of a young woman with her first presentation to hospital due to a hypoglycemia and she underwent 2 excised fibroadenomas in the same breast before diagnosed of malignant phyllodes tumor. She was complaining about 2 masses presented in her right breast 4 months after mastectomy.
Diagnoses:
Recurrent phyllodes tumor of the breast.
Interventions:
We conducted an immediate autologous myocutaneous flap transplantation after a wide-excision. Postoperative radiotherapy was recommended.
Outcomes:
She was in good general condition without tumor relapses during 8 months of follow-up.
Lessons:
Recurrent fibroadenomas in the same breast, especially those of large size with rapid growth rate, suggesting a high transformation possibility from fibroadenoma to phyllodes tumor. We recommend an extended tumor resection and immediate or delayed reconstruction of the breast for the recurrent phyllodes tumor with separately multiple relapses.
Related Concept Videos
02:07Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
01:24Disorders of the Female Reproductive System