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Updated: Feb 16, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
A case report: Does the ulcer belong to esophageal carcinoma or HIV?
Ning Jia1, Yanping Tang, Yang Li
1Department of Gastroenterology, Tianjin Hospital of Integrated Traditional Chinese and Western Medicine Department of Diabetes, Tianjin Nankai District Hospital of Traditional Chinese Medicine Department of Preventive Treatment of Disease, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, China.
Rationale:
The deep-rooted pathogenesis of the human papilloma virus (HPV) infection is still uncertain and argumentative. As we know, a lot of cases of esophageal infections, such as esophageal squamous cell carcinoma (ESCC) and esophageal squamous papilloma (ESP), associated with HPV are reported. However, primary esophageal ulcer infection associated with HPV is unusual.
Patient Concerns:
This case is different from the other reports associated with HPV due to the patient's favorable prognosis.
Diagnoses:
We present a case of a man diagnosed in the Gastroenterology Department of Tianjin Hospital of Integrated Traditional Chinese and Western Medicine, which presented a deep and big esophageal ulcer with irregular borders caused by type 16 HPV infection.
Interventions:
The esophageal ulcer was treated with vidarabine monophosphate treatment.
Outcome:
The esophageal ulcer was cured.
Lessons:
We could put forward the diagnostic criteria available for diagnostic guidelines and 2 hypotheses that could possibly prevent esophageal carcinoma from happening.
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