Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

513
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
513
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

5.2K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complete pathological response in patients with bladder cancer: predictors and outcomes.

Therapeutic advances in urology·2026
Same author

Characterizing the Activity of Inflammasome-Related Genes and Their Association With Oncological Outcomes in Prostate Cancer.

The Prostate·2026
Same author

Emerging robotic platforms in partial nephrectomy: a comparative systematic review and network meta-analysis.

Journal of robotic surgery·2026
Same author

The first United States prospective trial using the Hugo™ robot-assisted surgery system.

BJU international·2026
Same author

Vietnamese cohort study on non-renal cell carcinoma kidney cancers: Identifying tumor size as an independent prognostic factor.

Urologia·2026
Same author

Outpatient <i>vs</i> Inpatient Robotic Partial Nephrectomy: A Systematic Review and Meta-Analysis.

Journal of endourology·2026

Related Experiment Video

Updated: Feb 16, 2026

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

34.0K

Inflammation on Prostate Needle Biopsy is Associated with Lower Prostate Cancer Risk: A Meta-Analysis.

Shaleen R Vasavada1, Ryan W Dobbs1, André A Kajdacsy-Balla1

  • 1Departments of Urology and Pathology (AAK-B), University of Illinois at Chicago, Chicago, Illinois.

The Journal of Urology
|December 17, 2017
PubMed
Summary
This summary is machine-generated.

Inflammation found on prostate needle biopsies is linked to a reduced risk of developing prostate cancer. This finding suggests inflammation may be a protective factor against future prostate cancer diagnoses.

Keywords:
biopsyinflammationprostate-specific antigenprostatic neoplasmsrisk factors

More Related Videos

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
05:35

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

1.7K
Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking
07:34

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Published on: November 17, 2023

1.3K

Related Experiment Videos

Last Updated: Feb 16, 2026

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

34.0K
Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
05:35

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

1.7K
Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking
07:34

Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

Published on: November 17, 2023

1.3K

Area of Science:

  • Urology
  • Oncology
  • Pathology

Background:

  • Prostate cancer is a leading cause of cancer death in men.
  • The role of inflammation in prostate cancer development is not fully understood.
  • Prostate needle biopsies are a common diagnostic tool.

Purpose of the Study:

  • To evaluate the association between inflammation on prostate needle biopsies and the risk of prostate cancer.
  • To synthesize existing research through a comprehensive literature review and meta-analysis.

Main Methods:

  • Searched Embase, PubMed, and Web of Science from 1990 to 2016 for relevant studies.
  • Included original research with adult human subjects, cohort or case-control designs, and histological data on inflammation and prostate cancer.
  • Performed a meta-analysis using random effects models to calculate combined odds ratios (ORs) and 95% confidence intervals (CIs).

Main Results:

  • Analyzed 25 studies involving 20,585 subjects and 6,641 prostate cancer patients.
  • Found that any inflammation on prostate needle biopsy was significantly associated with a lower prostate cancer risk (OR 0.455, 95% CI 0.337-0.573).
  • Both acute (OR 0.681, 95% CI 0.450-0.913) and chronic inflammation (OR 0.499, 95% CI 0.334-0.665) were individually linked to reduced prostate cancer risk.

Conclusions:

  • Inflammation detected on prostate needle biopsies is associated with a decreased risk of prostate cancer.
  • The presence of inflammation may indicate a lower likelihood of a subsequent prostate cancer diagnosis.
  • These findings highlight a potential protective role of inflammation in prostate cancer development.