Percutaneous drug-eluting balloon angioplasty to treat dialysis access stenosis
Mafalda Massara1, Pietro Finocchiaro2, Alberto Volpe3
1Vascular Surgery Unit, Bianchi-Melacrino-Morelli Hospital, Via Melacrino 1, Reggio Calabria, Italy.
Insights
Drug-eluting balloon angioplasty shows promise for treating dialysis access stenosis, a common complication of arteriovenous fistulas. This endovascular therapy demonstrated significant primary patency rates at one and two years in a recent study.
Area of Science:
- Vascular Surgery
- Interventional Nephrology
- Medical Devices
Background:
- Arteriovenous fistulas are crucial for hemodialysis access.
- Conduit stenosis is a frequent complication, leading to reduced function and potential thrombosis.
- Endovascular therapy is preferred over open repair for dialysis access stenosis due to lower morbidity.
Purpose of the Study:
- To evaluate the efficacy of drug-eluting balloon angioplasty for treating dialysis access stenosis.
- To assess the primary patency rates following this intervention.
Main Methods:
- A study involving 18 consecutive patients with dialysis access stenosis.
- Application of drug-eluting balloon angioplasty.
- Calculation of primary patency rates at 1 and 2 years.
Main Results:
- Primary patency rate of 82% at 1 year.
- Primary patency rate of 68% at 2 years.
- Drug-eluting balloon angioplasty demonstrated favorable outcomes in managing dialysis access stenosis.
Conclusions:
- Drug-eluting balloon angioplasty is an effective treatment option for dialysis access stenosis.
- The intervention offers durable patency, reducing the recurrence of stenosis.
- This approach holds potential for improving hemodialysis access longevity.
Abstract:
A common complication of arteriovenous fistula for hemodialysis is development of conduit stenosis, which compromises function and can result in access thrombosis. Possible treatment options include open repair and endovascular therapy, with the latter preferred due to lower morbidity and similar outcomes. Recurrence of conduit stenosis is common and, based on the pathophysiology of this lesion, the application of drug-coated balloon angioplasty is attractive. In this report, the application of drug-eluting balloon angioplasty for dialysis access stenosis in 18 consecutive patients is detailed and primary patency rates of 82% at 1 year and 68% at 2 years were calculated.
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