Percutaneous drug-eluting balloon angioplasty to treat dialysis access stenosis

Mafalda Massara1, Pietro Finocchiaro2, Alberto Volpe3

  • 1Vascular Surgery Unit, Bianchi-Melacrino-Morelli Hospital, Via Melacrino 1, Reggio Calabria, Italy.

Insights

Drug-eluting balloon angioplasty shows promise for treating dialysis access stenosis, a common complication of arteriovenous fistulas. This endovascular therapy demonstrated significant primary patency rates at one and two years in a recent study.

Area of Science:

  • Vascular Surgery
  • Interventional Nephrology
  • Medical Devices

Background:

  • Arteriovenous fistulas are crucial for hemodialysis access.
  • Conduit stenosis is a frequent complication, leading to reduced function and potential thrombosis.
  • Endovascular therapy is preferred over open repair for dialysis access stenosis due to lower morbidity.

Purpose of the Study:

  • To evaluate the efficacy of drug-eluting balloon angioplasty for treating dialysis access stenosis.
  • To assess the primary patency rates following this intervention.

Main Methods:

  • A study involving 18 consecutive patients with dialysis access stenosis.
  • Application of drug-eluting balloon angioplasty.
  • Calculation of primary patency rates at 1 and 2 years.

Main Results:

  • Primary patency rate of 82% at 1 year.
  • Primary patency rate of 68% at 2 years.
  • Drug-eluting balloon angioplasty demonstrated favorable outcomes in managing dialysis access stenosis.

Conclusions:

  • Drug-eluting balloon angioplasty is an effective treatment option for dialysis access stenosis.
  • The intervention offers durable patency, reducing the recurrence of stenosis.
  • This approach holds potential for improving hemodialysis access longevity.

Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
374
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
2.0K
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
573
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
1.0K