Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Toxins01:36

Types of Toxins

3.7K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
3.7K
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

619
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
619
Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

649
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
649
Regulation of Stroke Volume01:27

Regulation of Stroke Volume

5.3K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
5.3K
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

624
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
624

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Associations of bilirubin, albumin, and the ALBI index with gastric cancer risk: a smoking-stratified prospective cohort study in men.

BMC gastroenterology·2026
Same author

Adiponectin as a Predictor of Metabolic Dysfunction-Associated Steatotic Liver Disease and Non-Alcoholic Fatty Liver Disease: A 17-Year Korean Cohort Study (Diabetes Metab J 2026;50:331-42).

Diabetes & metabolism journal·2026
Same author

Respiratory sound analysis for ICU clinical decision support: deep learning-based classification of normal and abnormal sounds using real ICU data.

BMC medical informatics and decision making·2026
Same author

Ethnic Heterogeneity in Reproductive Risk Factors for Breast Cancer, With a Focus on Asian Populations: A Meta-analysis.

Journal of cancer prevention·2026
Same author

Sex-specific associations of creatinine and antioxidant biomarkers with lung cancer risk by drinking and smoking behavior: A prospective cohort study.

Cancer epidemiology·2026
Same author

Mixed-model and transcriptome-wide association analyses identify transcription factors and genes associated with colorectal cancer susceptibility.

Nature communications·2026

Related Experiment Video

Updated: Feb 16, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

15.6K

Serum persistent organic pollutants levels and stroke risk.

Jung-Eun Lim1, Sunju Lee2, Sunmi Lee3

  • 1Institute for Health Promotion & Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, South Korea; College of Pharmacy, Ewha Womans University, South Korea.

Environmental Pollution (Barking, Essex : 1987)
|December 18, 2017
PubMed
Summary

Elevated levels of persistent organic pollutants (POPs), including specific PCBs, are linked to a significantly increased risk of stroke, particularly ischemic stroke. This study highlights environmental factors contributing to stroke incidence.

Keywords:
Endocrine disruptorsPolychlorinated biphenylsProspective studiesStroke

More Related Videos

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
16:02

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

3.3K
PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke
12:01

PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke

Published on: June 14, 2018

13.3K

Related Experiment Videos

Last Updated: Feb 16, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

15.6K
Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
16:02

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

3.3K
PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke
12:01

PET Imaging of Neuroinflammation Using [11C]DPA-713 in a Mouse Model of Ischemic Stroke

Published on: June 14, 2018

13.3K

Area of Science:

  • Environmental Health
  • Epidemiology
  • Toxicology

Background:

  • Limited understanding of environmental risk factors for stroke.
  • Persistent Organic Pollutants (POPs) are widespread environmental contaminants.
  • Investigating POPs' role in stroke etiology is crucial for public health.

Purpose of the Study:

  • To evaluate the association between serum persistent organic pollutants (POPs) levels and stroke risk.
  • To identify specific POPs contributing to stroke incidence.
  • To explore the relationship between POPs and different stroke subtypes.

Main Methods:

  • Case-cohort study design utilizing the Korean Cancer Prevention Study-II.
  • Measurement of serum POPs using gas chromatography/high-resolution mass spectrometry.
  • Weighted Cox regression analysis adjusted for multiple confounding factors.

Main Results:

  • Increased stroke risk associated with higher serum concentrations of p,p'-DDE, PCB118, PCB156, and PCB138.
  • Elevated Toxic Equivalency (TEQ) levels correlated with a threefold increase in stroke risk.
  • Positive association observed between Polychlorinated Biphenyls (PCBs) and ischemic stroke, but not hemorrhagic stroke.

Conclusions:

  • Elevated serum POPs levels are a significant risk factor for stroke.
  • Specific POPs and their combined toxic equivalency are implicated in stroke development.
  • Findings emphasize the need to reduce environmental exposure to POPs for stroke prevention.