Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Pulmonary Cycle: Exhalation

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

The Bronchial Tree

The Bronchial Tree

The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same journal

Pancreatic serous cystadenoma masquerading as malignancy.

BMJ case reports·2026

Same journal

Multidisciplinary management of pregnancy in Fowler's syndrome: sacral neuromodulation deactivation and innovative bladder care.

BMJ case reports·2026

Same journal

Maxillary hypoplasia and severe dental abnormalities in an adolescent cancer survivor after anticancer therapy.

BMJ case reports·2026

Same journal

Delayed diagnosis of a cervical DISH fracture leading to dropped head deformity treated with combined anterior-posterior stabilisation.

BMJ case reports·2026

Same journal

Managing nusinersen therapy during pregnancy in spinal muscular atrophy type 3.

BMJ case reports·2026

Same journal

Lower gastrointestinal bleeding (haematochezia) as the initial clue to disseminated histoplasmosis with central nervous system involvement in a renal transplant recipient.

BMJ case reports·2026

Search research articles

Related Experiment Video

Updated: Feb 16, 2026

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

Published on: August 30, 2019

Constrictive bronchiolitis presenting with a mixed obstructive and restrictive pattern, associated with acid reflux.

Kristen Capel¹, Richard Dee Shih¹

¹Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA.

BMJ Case Reports

|December 18, 2017

Summary

Silent gastroesophageal reflux disease (GERD) can cause constrictive bronchiolitis, a rare small airway disease. This case highlights the importance of GERD screening in patients with unexplained lung conditions.

Area of Science:

Pulmonology
Gastroenterology
Internal Medicine

Background:

Dyspnea on exertion in a previously healthy 55-year-old woman.

Keywords:

bronchiolitos interstitial lung disease lung function

More Related Videos

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

Related Experiment Videos

Last Updated: Feb 16, 2026

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

Published on: August 30, 2019

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

Pulmonary function tests revealed hyperinflation and air trapping, with inconclusive initial biopsies.

High-resolution CT showed mosaic attenuation, suggesting small airway disease.