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Updated: Feb 16, 2026

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Occult catheter rupture causing episodic symptoms in a patient treated with epoprostenol
Barbara L LeVarge1, Anica C Law2, Blanche Murphy3
11 6797 Pulmonary Diseases and Critical Care Medicine, University of North Carolina , Chapel Hill, NC, USA.
Abstract:
Infection, thrombosis, and catheter dislodgment are well-recognized potential complications of chronic intravenous prostanoid therapy for pulmonary arterial hypertension. As long-term outcomes of pulmonary hypertension patients improve, novel adverse events are likely to arise. We describe the sudden development of unexplained hypotension and lightheadedness in a patient receiving intravenous epoprostenol for several years, ultimately determined to be due to an unusual catheter complication, not previously described in this population.
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