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[Participation of the cholinergic system in the development of hemodynamic effects of GABA, administered

L N Shapoval, L S Pobegaĭlo

Fiziologicheskii Zhurnal SSSR Imeni I. M. Sechenova

|January 1, 1989

Abstract:

Acute experiments in cats revealed effects of GABA injections (2.10(-5)-5.10(-5) M/l) into the neuronal structures of the dorso-medial medulla after M-cholinoreceptors had been blocked. Hypotensive action of GABA injected into the n. ambiguous and ventral reticular nucleus was shown to be actualized through participation of bulbar M-cholinoreceptors. Effects of GABA injected into n. tractus solitarius occurred with no consistent participation of the central M-cholinoreceptors.

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