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Advanced research on deep brain stimulation in treating mental disorders
Dongxin Wang1, Xuejun Liu1, Bin Zhou2
1Mental Health Institute of Hunan Province, The Brain Hospital of Hunan Province, Changsha, Hunan 410007, P.R. China.
Experimental and Therapeutic Medicine
|December 19, 2017
Summary
Deep brain stimulation (DBS) offers a minimally invasive treatment for movement and mental health disorders. Further research is needed to confirm its efficacy and establish strict ethical guidelines for patient and target selection.
Area of Science:
- Neurology
- Neurosurgery
- Psychiatry
Background:
- Deep brain stimulation (DBS) is a stereotactic technique using electrical brain stimulation.
- It is minimally invasive, safe, adjustable, and reversible.
- DBS is effective for movement disorders and shows promise for mental health conditions.
Purpose of the Study:
- To review the mechanisms of DBS.
- To discuss target selection, side effects, ethical considerations, and risks.
- To highlight DBS as a novel treatment for refractory mental illnesses.
Main Methods:
- Literature review of existing studies on deep brain stimulation.
- Analysis of reported outcomes for various neurological and psychiatric conditions.
- Examination of ethical arguments and patient selection criteria.
Main Results:
- DBS is widely applied for movement disorders with promising results.
- Encouraging effects have been reported for mental symptoms like anxiety and depression.
- DBS is being explored for depression, OCD, Tourette's syndrome, and other refractory conditions.
Conclusions:
- Deep brain stimulation is a developing and promising therapeutic option.
- Extensive research is required to ascertain its full curative potential.
- Strict ethical standards are essential for patient and target selection in DBS.
