Post-Ictal Transient Atrial Fibrillation As A Rare Manifestation Of Grand Mal Seizure

Gulshan Man Singh Dangol1,2, David A Hoffman1,2

  • 1Northeast Ohio Medical University. Department of Medicine. Rootstown, Ohio.

Insights

Transient atrial fibrillation (AF) can occur after generalized tonic-clonic seizures (GTCS). This rare complication requires careful consideration of anticoagulation risks versus benefits in epileptic patients.

Area of Science:

  • Cardiology
  • Neurology

Background:

  • Atrial fibrillation (AF) is commonly linked to various conditions like valvular disease, coronary artery disease, hyperthyroidism, alcohol, and pulmonary embolism.
  • Transient AF is a rare manifestation that can arise from generalized tonic-clonic seizures (GTCS).

Observation:

  • A 33-year-old male presented with GTCS and AF exhibiting a rapid ventricular response.
  • Initial diagnostic workup, including cardiac enzymes, thyroid function, and echocardiogram, revealed no abnormalities.
  • The patient converted to sinus rhythm spontaneously after diltiazem administration for rate control.

Findings:

  • This case highlights a rare instance of AF occurring immediately post-GTCS.
  • The patient had no prior history of AF or seizures.

Implications:

  • AF following seizures is an uncommon but significant clinical observation in patients with epilepsy.
  • The decision to initiate anticoagulation for AF must be carefully balanced against the increased risk of intracranial hemorrhage in patients prone to seizures.

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