Post-Ictal Transient Atrial Fibrillation As A Rare Manifestation Of Grand Mal Seizure
Gulshan Man Singh Dangol1,2, David A Hoffman1,2
1Northeast Ohio Medical University. Department of Medicine. Rootstown, Ohio.
Insights
Transient atrial fibrillation (AF) can occur after generalized tonic-clonic seizures (GTCS). This rare complication requires careful consideration of anticoagulation risks versus benefits in epileptic patients.
Area of Science:
- Cardiology
- Neurology
Background:
- Atrial fibrillation (AF) is commonly linked to various conditions like valvular disease, coronary artery disease, hyperthyroidism, alcohol, and pulmonary embolism.
- Transient AF is a rare manifestation that can arise from generalized tonic-clonic seizures (GTCS).
Observation:
- A 33-year-old male presented with GTCS and AF exhibiting a rapid ventricular response.
- Initial diagnostic workup, including cardiac enzymes, thyroid function, and echocardiogram, revealed no abnormalities.
- The patient converted to sinus rhythm spontaneously after diltiazem administration for rate control.
Findings:
- This case highlights a rare instance of AF occurring immediately post-GTCS.
- The patient had no prior history of AF or seizures.
Implications:
- AF following seizures is an uncommon but significant clinical observation in patients with epilepsy.
- The decision to initiate anticoagulation for AF must be carefully balanced against the increased risk of intracranial hemorrhage in patients prone to seizures.
Abstract:
Atrial fibrillation (AF) most frequently occurs as a consequence of multiple etiologies including valvular disease, coronary artery disease, hyperthyroidism, alcohol ingestion, and pulmonary embolism. However, on rare occasion transient AF may be a result of generalized tonic-clonic seizures (GTCS). A 33-year-old-man presented to the emergency department following GTCS in AF with rapid ventricular response. He had no previous documented history. Diagnostic evaluation including electrolytes, thyroid function, cardiac enzymes, serum and urine drug screen, and two-dimensional echocardiogram were unremarkable. Diltiazem was initiated for rate control with spontaneous conversion to sinus rhythm with no recurrence. AF post-seizure is a rare phenomenon but should be considered in epileptic patients. Anticoagulation must be considered in AF due to the risk of cardioembolic stroke but should be weighed against the potential risk of head injury and subsequent intracranial bleed in patients with grand mal seizures.
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