Mating call phonotaxis in female American toad: lesions of anterior preoptic nucleus

Lesions of the preoptic area and immediately adjacent septal area were made in female American toads, Bufo americanus. The ability to show mating call phonotaxis (MCP) was then tested for. The intensity of MCP was found to decrease as the degree of damage to the anterior tip of the anterior preoptic nucleus (APON) increased. The APON is known to concentrate androgens and to be essential for mating calling by male anurans. Perhaps the APON is involved also in the detection of the elevated levels of prostaglandin associated with MCP. Even in lesioned toads in which phonotaxis was nearly absent, there was an occasional MCP response that seemed entirely normal. Therefore, the APON is not involved in generating or guiding the motor mechanisms of phonotaxis.