Related Experiment Video
Updated: Feb 16, 2026

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration
Published on: September 29, 2018
Progression and Treatment of Bilateral Knee Bone Marrow Edema Syndrome: A Case Report
Daniel Miranian1, Nathan Lanham1, J Derek Stensby2
1515 Ray C. Hunt Drive, Suite 1100, Charlottesville, VA 22903. E-mail address for D. Miranian: dcm4ca@virginia.edu. E-mail address for N. Lanham: nsl2e@virginia.edu. E-mail address for D. Diduch: drd5c@virginia.edu.
Case:
We report the case of a patient with bilateral multicompartmental bone marrow edema syndrome of the knee, which responded favorably to subchondral core decompression after failing to respond to nonoperative treatment.
Conclusion:
This case demonstrates that subchondral core decompression can be effective for the treatment of bone marrow edema syndrome.
