Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

591
Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
591
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

727
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
727
Molecular Models02:00

Molecular Models

44.0K
Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
44.0K
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

7.1K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.1K
Distribution of Molecular Speeds01:27

Distribution of Molecular Speeds

5.6K
The motion of molecules in a gas is random in magnitude and direction for individual molecules, but a gas of many molecules has a predictable distribution of molecular speeds. This predictable distribution of molecular speeds is known as the Maxwell-Boltzmann distribution. The distribution of molecular speeds in liquids is comparable to that of gases but not identical and can help to understand the phenomenon of the boiling and vapor pressure of a liquid. Consider that a molecule requires a...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Progestogen priming is not essential to trigger ovulation in seasonal anoestrus ewes injected twice with a synthetic kisspeptin analogue.

Animal : an international journal of animal bioscience·2026
Same author

Proton pump inhibitors and risk of fracture in older adults: a systematic review and meta-analysis.

Geriatric nursing (New York, N.Y.)·2025
Same author

Ongoing multiparameter unrest at the Montagne Pelée volcano on Martinique from 2019 to 2024.

Scientific reports·2025
Same author

Fungal Planet description sheets: 1697-1780.

Fungal systematics and evolution·2025
Same author

What are the 100 most cited fungal genera?

Studies in mycology·2024
Same author

A genome-informed higher rank classification of the biotechnologically important fungal subphylum <i>Saccharomycotina</i>.

Studies in mycology·2024

Related Experiment Video

Updated: Feb 16, 2026

Visualization and Quantification of High-Dimensional Cytometry Data using Cytofast and the Upstream Clustering Methods FlowSOM and Cytosplore
06:01

Visualization and Quantification of High-Dimensional Cytometry Data using Cytofast and the Upstream Clustering Methods FlowSOM and Cytosplore

Published on: December 12, 2019

9.0K

fMLC: fast multi-level clustering and visualization of large molecular datasets.

D Vu1, S Georgievska2, S Szoke1

  • 1Bioinformatics group, Westerdijk Fungal Biodiversity Institute, 3584CT Utrecht, The Netherlands.

Bioinformatics (Oxford, England)
|December 19, 2017
PubMed
Summary

A new tool, fMLC, clusters DNA sequences rapidly, overcoming limitations in large biological datasets. This DNA sequence analysis is twelve times faster than previous methods.

More Related Videos

ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data
05:12

ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data

Published on: January 16, 2019

11.9K
Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

12.2K

Related Experiment Videos

Last Updated: Feb 16, 2026

Visualization and Quantification of High-Dimensional Cytometry Data using Cytofast and the Upstream Clustering Methods FlowSOM and Cytosplore
06:01

Visualization and Quantification of High-Dimensional Cytometry Data using Cytofast and the Upstream Clustering Methods FlowSOM and Cytosplore

Published on: December 12, 2019

9.0K
ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data
05:12

ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data

Published on: January 16, 2019

11.9K
Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry
11:14

Rapid High-throughput Species Identification of Botanical Material Using Direct Analysis in Real Time High Resolution Mass Spectrometry

Published on: October 2, 2016

12.2K

Area of Science:

  • Bioinformatics
  • Computational Biology

Background:

  • Current data clustering and visualization methods struggle to scale with large biological datasets, hindering molecular sequence identification.
  • Efficient analysis of extensive molecular sequence data is crucial for biological research.

Purpose of the Study:

  • To introduce fMLC, a novel multi-threaded tool for clustering DNA sequences.
  • To present DiVE, an interactive web-based visualization component complementing fMLC.
  • To address the scalability challenge in analyzing large biological sequence datasets.

Main Methods:

  • Development of a multi-threaded tool (fMLC) for DNA sequence clustering.
  • Integration of an interactive web-based visualization component (DiVE).
  • Application of fMLC to cluster 350,000 ITS fungal sequences at the species level.

Main Results:

  • fMLC successfully clustered 350,000 ITS fungal sequences at the species level.
  • The comparison and clustering process for the dataset was completed in under two hours.
  • fMLC demonstrated a twelve-fold increase in speed compared to previously reported methods.

Conclusions:

  • fMLC offers a scalable and efficient solution for clustering large DNA sequence datasets.
  • The combined fMLC and DiVE system significantly accelerates molecular sequence identification and analysis.
  • This advancement facilitates deeper insights into fungal diversity and molecular biology.