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Anti-inflammatory steroid use in impacted third molar surgery: a systematic review
G Varvara1, S Bernardi2, T Cutilli2
1Department of Medical, Oral and Biotechnological Sciences, G. dAnnunzio University of Chieti-Pescara, Chieti, Italy.
Journal of Biological Regulators and Homeostatic Agents
|December 20, 2017
Summary
Corticosteroids effectively manage post-operative inflammation in oral surgery. This review guides clinicians on their appropriate use and administration to improve healing outcomes.
Area of Science:
- Oral Surgery
- Pharmacology
- Inflammation Management
Background:
- Oral surgery causes tissue trauma, potentially leading to post-operative inflammation that impedes healing.
- Nonsteroidal anti-inflammatory drugs and corticosteroids are key pharmacological agents for managing this inflammation.
- Corticosteroids target distinct molecular pathways involved in the inflammatory cascade.
Discussion:
- This systematic review analyzes various corticosteroids used in oral surgery.
- It examines their specific indications and optimal routes of administration.
- The goal is to create a clinical framework for effective post-operative inflammation management.
Key Insights:
- Corticosteroids are valuable in mitigating post-operative inflammatory sequelae following oral surgical procedures.
- Understanding different corticosteroid types, indications, and administration routes is crucial for clinicians.
- Evidence from randomized controlled trials (RCTs) published between 2007-2017 informs clinical practice.
Outlook:
- Further research may refine optimal corticosteroid protocols for specific oral surgery types.
- Integration of these findings can enhance patient recovery and reduce complications.
- This review provides a foundation for evidence-based pharmacological management in oral surgery.
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