Varicella epidemiology in Latin America and the Caribbean

Maria L Ávila-Agüero1, Sandra Beltrán2, José Brea Del Castillo3

  • 1a Servicio de Infectología del Hospital Nacional de Niños, 'Carlos Sáenz-Herrera , Pediatra Infectóloga , San José , Costa Rica.

Expert Review of Vaccines
|December 20, 2017
PubMed

Insights

Implementing the varicella vaccine in national immunization programs across Latin America and the Caribbean (LAC) is crucial. This strategy will significantly reduce the disease burden of varicella in children throughout the region.

Area of Science:

  • Pediatric Infectious Diseases
  • Vaccinology
  • Public Health

Background:

  • Varicella (chickenpox) is a vaccine-preventable infectious disease prevalent in Latin America and Caribbean (LAC) countries.
  • While often considered benign, varicella can lead to complications, necessitating effective prevention strategies.

Purpose of the Study:

  • To summarize key aspects of varicella in the LAC region.
  • To advocate for the inclusion of the varicella vaccine in national immunization programs.
  • To evaluate the impact of varicella vaccination on disease burden.

Main Methods:

  • A systematic review of medical evidence on varicella disease burden, prevention programs, and vaccine characteristics in LAC.
  • Review of national varicella prevention vaccination programs and their epidemiological impact.
  • Inclusion of updated data from additional countries in the region.

Main Results:

  • Varicella is a vaccine-preventable disease with significant public health implications in LAC.
  • The systematic review analyzed vaccine immunogenicity, efficacy, effectiveness, and safety.
  • Data on national program impacts on varicella epidemiology were assessed.

Conclusions:

  • Incorporating a two-dose varicella vaccine into national immunization schedules across LAC offers substantial health benefits for children.
  • Widespread vaccination is essential for reducing the overall disease burden of varicella in the region.
Abstract

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