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Varicella epidemiology in Latin America and the Caribbean
Maria L Ávila-Agüero1, Sandra Beltrán2, José Brea Del Castillo3
1a Servicio de Infectología del Hospital Nacional de Niños, 'Carlos Sáenz-Herrera , Pediatra Infectóloga , San José , Costa Rica.
Insights
Implementing the varicella vaccine in national immunization programs across Latin America and the Caribbean (LAC) is crucial. This strategy will significantly reduce the disease burden of varicella in children throughout the region.
Area of Science:
- Pediatric Infectious Diseases
- Vaccinology
- Public Health
Background:
- Varicella (chickenpox) is a vaccine-preventable infectious disease prevalent in Latin America and Caribbean (LAC) countries.
- While often considered benign, varicella can lead to complications, necessitating effective prevention strategies.
Purpose of the Study:
- To summarize key aspects of varicella in the LAC region.
- To advocate for the inclusion of the varicella vaccine in national immunization programs.
- To evaluate the impact of varicella vaccination on disease burden.
Main Methods:
- A systematic review of medical evidence on varicella disease burden, prevention programs, and vaccine characteristics in LAC.
- Review of national varicella prevention vaccination programs and their epidemiological impact.
- Inclusion of updated data from additional countries in the region.
Main Results:
- Varicella is a vaccine-preventable disease with significant public health implications in LAC.
- The systematic review analyzed vaccine immunogenicity, efficacy, effectiveness, and safety.
- Data on national program impacts on varicella epidemiology were assessed.
Conclusions:
- Incorporating a two-dose varicella vaccine into national immunization schedules across LAC offers substantial health benefits for children.
- Widespread vaccination is essential for reducing the overall disease burden of varicella in the region.
Introduction:
The Latin American Society of Pediatric Infectious Diseases (SLIPE), with the support of the Americas Health Foundation (AHF), has developed a position paper on varicella prevention in Latin America and Caribbean countries (LAC). This article summarizes the most relevant aspects of varicella in LAC, and emphasizes the need to include the varicella vaccine in the national immunization programs in the Region and evaluate its impact disease burden.
Areas Covered:
A systematic review was conducted of the medical evidence published and presented at various regional medical conferences on the disease burden in LAC, the advances made by prevention programs, the available vaccines in the Region, and their immunogenicity, efficacy, effectiveness, and safety. The different national varicella-prevention vaccination programs were reviewed, as was available information regarding the impact of these programs on the epidemiology of varicella in those countries implementing a varicella vaccine strategy. Following that initial publication, an update was conducted, including data from additional countries in the Region.
Expert Commentary:
Varicella is a vaccine-preventable infectious disease, considered a 'benign disease' because of lower complication rates when compared with measles, pertussis. The incorporation of a two-dose varicella vaccine in national immunization schedules in all countries throughout LAC would be of great benefit to the health of the children.
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