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Deep Brain Stimulation for Parkinson Disease Dementia: A New Frontier?

Wissam Deeb1, Michael S Okun1, Leonardo Almeida1

  • 1Center for Movement Disorders and Neurorestoration, Department of Neurology, University of Florida, Gainesville.

JAMA Neurology
|December 20, 2017
PubMed
Abstract

No abstract available in PubMed .

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Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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