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Proofreading

Proofreading

Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore, it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase...

Proofreading

Proofreading

Clot Retraction and Fibrinolysis

Clot Retraction and Fibrinolysis

After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.

Mismatch Repair

Mismatch Repair

Mismatch Repair

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...

Long-patch Base Excision Repair

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:

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Updated: Feb 16, 2026

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

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Erratum

Medico-Chirurgical Journal : Or, Quarterly Register of Medical and Surgical Science

|December 20, 2017

Summary

This summary is machine-generated.

This study provides a correction to previously published research. The erratum ensures the accuracy of scientific records for future reference and reliable data interpretation.

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Area of Science:

Scientific publishing
Academic errata
Research integrity

Context:

Correction of a specific article
Ensuring data accuracy
Maintaining scholarly record

Purpose:

To rectify an error in a published article
To improve the reliability of scientific literature
To provide accurate information to researchers

Summary:

An official correction has been issued for an article published on page 277, volume 1.
This erratum addresses a specific inaccuracy within the original publication.
The correction is essential for the integrity of the scientific record.

Impact:

Enhances the credibility of the scientific journal
Prevents misinterpretation of data by readers
Upholds standards of scientific accuracy and transparency