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Diversification of Protein Cage Structure Using Circularly Permuted Subunits

Yusuke Azuma1, Michael Herger1, Donald Hilvert1

  • 1Laboratory of Organic Chemistry, ETH Zurich , 8093 Zurich, Switzerland.

Journal of the American Chemical Society
|December 20, 2017
PubMed
Summary

Researchers engineered a circularly permuted lumazine synthase (cpAaLS) protein to create versatile protein cages. This novel building block allows for tunable structures and diverse applications in biotechnology and medicine.

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