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Updated: Feb 16, 2026

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate
Published on: September 11, 2013
Topiramate-induced macular neurosensory retinal detachment
Kevin Rosenberg1, Joseph Maguire2, Joseph Benevento3
1Retina Vitreous Surgeons of Central New York, 3107 East Genesee Street, Syracuse, NY 13066, USA.
Purpose:
To present a previously unreported retinal side-effect from topiramate use in two cases.
Observations:
Macular neurosensory retinal detachments were seen in two patients shortly after beginning oral topiramate. The macular detachments resolved shortly after discontinuing this medication.
Conclusions And Importance:
As these two cases represent the first reports of topiramate-induced macular neurosensory retinal detachment, clinicians should be aware of this potential ocular side effect when administering this medication.
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