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Related Experiment Video

Updated: Feb 16, 2026

Author Spotlight: Advancing Corneal Innervation Research Through Innovative Models

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Published on: December 8, 2023

A stepping stone in treating dendritic keratitis.

Hosam Sheha^1,2, Sean Tighe^1,2, Anny M S Cheng^1,2

¹Ocular Surface Center, Miami, FL, USA.

American Journal of Ophthalmology Case Reports

|December 21, 2017

Summary

This summary is machine-generated.

Self-retained amniotic membrane after debridement effectively treats recurrent dendritic keratitis. This approach promotes corneal healing without scarring or recurrence, even with non-compliance to antiviral therapy.

Keywords:

Amniotic membrane Antiviral Dendritic keratitis Interferon

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Area of Science:

Ophthalmology
Regenerative Medicine

Background:

Recurrent dendritic keratitis poses a significant challenge in ophthalmic practice.
Standard treatments often involve antiviral medications and debridement, but recurrence and scarring can occur.

Observation:

A case study involving a 70-year-old female with recurrent dendritic keratitis.
Treatment consisted of debridement followed by the application of a self-retained amniotic membrane.
The patient demonstrated complete symptom resolution, reduced inflammation, and corneal re-epithelialization within five days.

Findings:

The self-retained amniotic membrane facilitated rapid corneal healing and visual acuity improvement.
The corneal surface remained stable for 18 months post-treatment, despite inconsistent antiviral medication use.
The amniotic membrane application showed potential anti-inflammatory and anti-scarring benefits.

Implications:

Self-retained amniotic membrane is a promising therapeutic option for dendritic keratitis.
Further research is warranted to explore the potential topical antiviral properties of amniotic membranes.
This method may offer a viable alternative for managing recurrent corneal infections, potentially reducing long-term complications.