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Inonotosis in Patient with Hematologic Malignancy
Emerging Infectious Diseases
|December 21, 2017
Abstract:
We report a lung-invasive fungal disease with possible cutaneous needle tract seeding in a patient with a febrile neutropenia caused by the Basidiomycetes mold Inonotus spp. Although rare, Inonotus spp. should be added to the list of microorganisms causing invasive fungal disease in neutropenic patients with hematologic malignancies.
Insights
A rare fungal infection caused by Inonotus mold occurred in a neutropenic patient. This finding suggests Inonotus species should be recognized as a cause of invasive fungal disease in immunocompromised individuals.
Area of Science:
- Mycology
- Infectious Diseases
- Hematology
Background:
- Neutropenic patients with hematologic malignancies are susceptible to invasive fungal infections.
- Basidiomycetes molds are an uncommon cause of invasive fungal disease in this population.
Observation:
- A case of lung-invasive fungal disease with possible cutaneous needle tract seeding is presented.
- The causative agent was identified as the Basidiomycetes mold Inonotus spp.
Findings:
- Inonotus spp. can cause invasive fungal disease in neutropenic patients.
- Cutaneous needle tract seeding is a potential route of infection for Inonotus spp.
Implications:
- Inonotus spp. should be considered in the differential diagnosis of invasive fungal disease in neutropenic patients.
- This case expands the spectrum of known fungal pathogens causing severe infections in immunocompromised hosts.
- Further research is warranted to understand the pathogenesis and treatment of Inonotus spp. infections.
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