Postmortem Findings in Patient with Guillain-Barré Syndrome and Zika Virus Infection
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Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice
Published on: October 17, 2018
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Emerging Infectious Diseases
|December 21, 2017
Abstract:
Postmortem examination results of a patient with Guillain-Barré syndrome and confirmed Zika virus infection revealed demyelination of the sciatic and cranial IV nerves, providing evidence of the acute demyelinating inflammatory polyneuropathy Guillain-Barré syndrome variant. Lack of evidence of Zika virus in nervous tissue suggests that pathophysiology was antibody mediated without neurotropism.
Keywords:
Guillain-Barré syndromePuerto RicoZika virusinfectious disease pathophysiologypostmortem investigationvector-borne infectionsviruses
