Related Experiment Video
Updated: Jan 10, 2026
Generation of Human Chimeric Antigen Receptor Regulatory T Cells
Published on: January 3, 2025
[Research Progress on Chimeric Antigen Receptor T Cells-Review]
1Southeast University Medical College, Department of Hematology of Zhongda Hospital Affiliated to Southeast University, Nanjing 210009, Jiangsu Province, China.
Abstract:
As more and more clinical trials about chimeric antigen receptor T cells (CAR-T) have been carried out successfully, the CAR-T are getting well-known. Thanks for genetic engineering, CAR-T has the tumor special antigen expressed on the surface. CAR-T therapy is the adoptive immunotheraphy for rapidly advancing tumors. This technology has made a great progress in both blood malignancies and solid tumor. However, CAR-T also meet many difficulties in the way of development. This review discusses the clinical application, challenges and developing trend of CAR-T.
