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Current methodological approaches in conditioned pain modulation assessment in pediatrics.
Philippe S Hwang1, My-Linh Ma1,2,3, Nora Spiegelberg1
1Shriners Hospital for Children - Canada.
Journal of Pain Research
|December 22, 2017
Summary
Conditioned pain modulation (CPM) research in children is limited but suggests pathway deficiencies may contribute to chronic pain. This review overviews current pediatric CPM studies for researchers and clinicians.
Area of Science:
- Neuroscience
- Pediatric Pain Research
Background:
- Conditioned pain modulation (CPM) is used to study pain processing in adults.
- Limited research exists on CPM in pediatric populations.
- Deficiencies in descending pain pathways may link to early-life chronic pain.
Purpose of the Study:
- To review existing CPM studies in pediatric populations.
- To provide an overview for clinicians and researchers on pediatric CPM.
- To discuss implications for individualizing pediatric pain treatment.
Main Methods:
- PubMed search for studies solely on pediatric populations.
- Review of 12 identified studies.
- Analysis of demographics, methodologies, and conclusions.
Main Results:
- Identified 12 studies focusing exclusively on pediatric CPM.
- Examined variations in study populations, methods, and outcomes.
- Highlighted the need for more research in this area.
Conclusions:
- CPM research in children is emerging but limited.
- Understanding pediatric CPM is crucial for pain management.
- CPM may help tailor treatments for pediatric pain syndromes.
